Fig. 8

Representative photomicrographs of the effect of Datura metel leaf extract on the medial prefrontal cortex neuronal cells. A: VEH; B: DM (200 mg/kg); C: DM (400 mg/kg); D: DM (800 mg/kg); Black Arrow– shows shrinking nerve cells in the treated groups compared with control, red arrow – neuronal vacuolation, blue arrow- cell body chromatolysis, yellow arrow – nuclear pyknosis. (H and E) stain; Mag: × 250; Calibration bar for all figures = 0.01 mm (10 µm) VEH Vehicle, DM Datura metel