Skip to main content

Table 1 Effect of Datura metel leaf extract on anxiety-like behaviour in mice using elevated plus maze (EPM)

From: Datura metel stramonium exacerbates behavioral deficits, medial prefrontal cortex, and hippocampal neurotoxicity in mice via redox imbalance

Treatment

Open arm entry

Open arm duration

% Open arm entry

% Open arm duration

Index of open arm avoidance

VEH10mL/kg

5.83 ± 0.48

73.17 ± 3.57

42.33 ± 2.99

24.39 ± 1.19

66.50 ± 1.29

DM 200 mg/kg

3.50 ± 0.43*

41.50 ± 3.13*

26.63 ± 2.23

13.83 ± 1.04*

79.61 ± 1.36*

DM400 mg/kg

2.83 ± 0.31*a

28.67 ± 2.40*a

21.47 ± 1.96*a

9.557 ± 0.80*a

84.49 ± 0.84*a

DM 800 mg/kg

1.67 ± 0.33*ab

17.00 ± 2.28*ab

14.85 1.87*ab

5.665 ± 0.76*ab

88.91 ± 1.32*ab

  1. Values are expressed as Mean ± SEM (n = 6) (One-way ANOVA followed by Bonferroni post hoc test). *, a, b p < 0.05 considered statistically significant when compared with the Control, Datura metel extract (200 mg/kg) and DM (400 mg/kg) treated groups, respectively VEH Vehicle, DM Datura metel
Back to article page

Laboratory Animal Research

ISSN: 2233-7660