Identification of proteins regulated by chlorogenic acid in an ischemic animal model: a proteomic approach

Table 1 List of identified differentially expressed proteins in vehicle and chlorogenic acid-treated animals with middle cerebral artery occlusion

Spot no	Protein name	Accession no	Mw (kDa)	pI	Mass matched	Sequence coverage (%)
1	Gamma enolase	P07323	47.14	5.00	14/70	35
2	Unknown
3	Rab, GTPase-GDP dissociation stimulation stimulator 1	P52306	66.32	5.20	20/156	53
4	Eukaryotic initiation factor 4A-II	Q5RKI1	46.37	5.33	16/82	40
5	Eukaryotic initiation factor 4A-II	Q5RKI1	46.37	5.33	16/82	40
6	Unknown	Q7TQ13	31.27	4.85	11/66	58
7	Rab GDP dissociation inhibitor beta	P50399	50.50	5.90	9/150	23
8	Rab GDP dissociation inhibitor beta	P50399	50.50	5.90	16/138	46
9	Protein phosphatase 2A, regulatory subunit B	P58389	36.59	5.88	9/56	29
10	Adenosylhomocysteinase	P10760	47.55	6.07	15/132	33
11	Thioredoxin	Q920J4	32.23	4.84	8/87	42
12	Mu-crystallin	Q9QYU4	33.53	5.34	9/86	24
13	Mu-crystallin	Q9QYU4	33.55	5.30	6/114	21
14	Mu-crystallin	Q9QYU4	33.53	5.34	9/86	24
15	Protein phosphatase 2A, subunit A	P63331	35.60	5.30	13/110	45
16	Unknown
17	Isocitrate dehydrogenase (NAD+) subunit alpha	Q99NA5	39.59	6.47	7/93	31
18	Isocitrate dehydrogenase (NAD+) subunit alpha	Q99NA5	39.59	6.47	7/108	21
19	Isocitrate dehydrogenase (NAD+) subunit alpha	Q99NA5	39.59	6.47	7/93	31
20	Dynamin-like protein 1	Q8K1M6	80.24	6.99	14/90	22
21	Glycerol-3-phosphate dehydrogenase	O35077	37.43	6.16	8/105	25
22	Peroxiredoxin 2	Q61171	21.64	5.30	9/51	46
23	Stathmin	P16949	49.93	5.35	9/23	21
24	Apolipoprotein A-I	P04693	30.04	5.25	16/116	50
25	Alpha-synuclein	P37377	14.50	4.70	6/134	43
26	UMP-CMP kinase	Q4KM73	22.16	5.66	10/114	50
27	Proteasome subunit β 4	P34067	29.18	6.45	78/13	42
28	Proteasome subunit alpha type3	P18422	28.40	5.30	7/112	27

Protein names and accession numbers are listed according to the SWISS-PROT database
MW molecular weight, pI isoelectric point

ISSN: 2233-7660