Ameliorative effect of hesperidin against high dose sildenafil-induced liver and testicular oxidative stress and altered gene expression in male rats

Table 2 Effect of HP on activities of serum AST, ALT, ALP and testosterone in SIL-treated rats

Parameters	Control	SIL	HP	SIL + HP
AST (U/ml)	30.66 ± 0.88	47.33 ± 2.18^a	30.32 ± 1.39^b	34.41 ± 1.38^b
ALT (U/ml)	40.66 ± 1.76	53.18 ± 1.45^a	40.04 ± 1.16^b	48.21 ± 2.18^b
ALP (U/ml)	62.66 ± 3.17	81.66 ± 2.31^a	60.24 ± 2.15^b	65.00 ± 1.19^b
Testosterone (ng/ml)	3.18 ± 0.61	1.27 ± 0.38^a	3.35 ± 0.41^b	2.62 ± 0.28^b

Values represent the mean ± SE of 6 rats. Values with the same letters are not significant at (P < 0.05)
^aP < 0.05: Significantly different from control
^bP < 0.05: Significantly different from SIL-treated group

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