Skip to main content

Table 1 Effect of shikimic acid on physiological measures of normal and diarrheal rats

From: Shikimic acid recovers diarrhea and its complications in SD rats fed lactose diet to induce diarrhea

Parameters

Control

Shikimic acid

Desmopressin drug

Diarrheal rats

Diarrheal rats + 

shikimic acid

Diarrheal rats + 

desmopressin

Total body weight

(g)

165  ± 6.24

167 ± 6.13

164 ± 6.52

128 ± 5.09a

163 ± 6.24b

162 ± 6.24b

Food consumption (g/day)

11.6 ± 1.2

11.4 ± 1.4

11.5 ± 1.6

7.2 ± 1.3a

11.3 ± 1.6b

11.2 ± 1.5b

Water intake

(ml/day)

12.4 ± 1.7

12.6 ± 1.5

12.3 ± 1.2

17.8 ± 1.3a

12.2 ± 1.7b

12.1 ± 1.7b

Liver weight

(g/100 g bw)

2.7 ± 0.08

2.6 ± 0.06

2.5 ± 0.09

1.8 ± 0.05a

2.4 ± 0.08b

2.3 ± 0.08b

Pancreas weight (g/100 g bw)

0.25 ± 0.03

0.27 ± 0.02

0.24 ± 0.04

0.16 ± 0.02a

0.23 ± 0.03b

0.22 ± 0.03b

Spleen weight

(g/100 g bw)

0.34 ± 0.06

0.33 ± 0.04

0.36 ± 0.05

0.21 ± 0.03a

0.32 ± 0.05b

0.31 ± 0.07b

Heart weight

(g/100 g bw)

0.36 ± 0.04

0.35 ± 0.06

0.38 ± 0.05

0.23 ± 0.03a

0.34 ± 0.03b

0.33 ± 0.03b

Fecal pellet count

38 ± 4.07

37 ± 3.86

36 ± 4.20

25 ± 3.14a

35 ± 4.35b

34 ± 4.26b

  1. Number of animals = 6 rats/group. Data are represented as mean ± SEM
  2. aHighly significant change compared to control
  3. bHighly significant change compared to diarrheal rats