From: Shikimic acid recovers diarrhea and its complications in SD rats fed lactose diet to induce diarrhea
Parameters | Control | Shikimic acid | Desmopressin drug | diarrheal rats | diarrheal rats + shikimic acid | diarrheal rats + desmopressin |
---|---|---|---|---|---|---|
Superoxide dismutase (U/g tissue) | 3250 ± 60 | 3240 ± 50 | 3245 ± 55 | 1170 ± 40b | 3230 ± 50d | 3220 ± 70d |
Glutathione peroxidase (U/g tissue) | 785 ± 19 | 780 ± 24 | 785 ± 21 | 365 ± 18b | 775 ± 16d | 770 ± 21d |
Catalase (µmol H2O2/ min/mg tissue) | 0.18 ± 0.05 | 0.19 ± 0.04 | 0.17 ± 0.06 | 0.09 ± 0.03b | 0.14 ± 0.06c | 0.15 ± 0.05c |
Malondialdehyde (µmol/g tissue) | 8.52 ± 0.60 | 8.49 ± 0.72 | 8.50 ± 0.69 | 19.38 ± 0.54b | 9.54 ± 0.83d | 9.58 ± 0.90d |
NADPH oxidase activity (mg/mg protein × 105) | 12.3 ± 1.18 | 12.5 ± 1.54 | 12.4 ± 1.37 | 8.6 ± 1.31a | 10.5 ± 1.25c | 10.7 ± 1.26c |
Conjugated dienes (μmol/g tissue) | 1.45 ± 0.19 | 1.42 ± 0.17 | 1.43 ± 0.15 | 1.86 ± 0.24a | 1.64 ± 0.19c | 1.62 ± 0.17c |
Oxidative index (A233/A215 ratio) | 0.49 ± 0.03 | 0.47 ± 0.05 | 0.50 ± 0.03 | 0.62 ± 0.04a | 0.54 ± 0.05c | 0.52 ± 0.06c |