Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans

Table 5 Comparison of the inner hair cell, outer hair cell, and spiral ganglion neuron count/density in humans and animals

Species	Inner hair cell count^a	Outer hair cell count^a	Spiral ganglion neuron count^a	References
Species	(Inner hair cell density^b)	(Outer hair cell density^b)	(Spiral ganglion neuron density^c)	References
Human	2936	11,650	33,383	Úlehlová et al. [112]
	(86)	(343)	(3.0–5.3)	Nelson and Hinojosa [113]
	(86)	(343)	(3.0–5.3)	Suzuki et al. [114]
Dog (beagle)	2775	10,702	NA	Sampaio et al. [115]
Dog (beagle)	(101)	(389)	(13.9–19.9)	Malkemper et al. [116]
Cat	2723	10,105	48,957^d	Lee et al. [117]
Cat	(99)	(373)	(NA)	Malkemper et al. [116]
Rabbit	1556	5,522	NA	Yuan et al. [107]
Rabbit	(107)	(381)	(NA)	Yuan et al. [107]
Monkey (Saimiri sciureus)	2134	8056	NA	Dayal and Bhattacharyya [118]
Monkey (Saimiri sciureus)	(NA)	(NA)	(NA)	Dayal and Bhattacharyya [118]
Guinea pig	2056	7377	NA	Burda [119]
Guinea pig	(100)	(361)	(17.9–18.4)^e	Wrzeszcz et al. [120]
Chinchilla	1827	7400	NA	Bhattacharyya and Dayal [121]
	(100)^d	(400)^d	(12.1–13.2)	Bohne and Carr [101]
	(100)^d	(400)^d	(12.1–13.2)	Takeno et al. [122]
Rat	959	3740	16,450	Keithley and Feldman [123]
	(NA)	(NA)	(15.7–18.6)	Burda et al. [99]
	(NA)	(NA)	(15.7–18.6)	McGuinness and Shepherd [124]
Mice	726	2466	7380	Burda et al. [99]
Mice	(121)	(411)	(35.5–39.4)^d	Irving et al. [125]

NA: Not available
^aNumber of cells per cochlea, unless specified
^bCellular densities in number of cells/mm along the length of the basilar membrane or organ of corti
^cCellular densities in number of cells/0.01 mm²
^dData withdrawn from the table/figure in the reference
^eRange adapted from mean ± 1 standard error

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