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Table 6 Comparison of the central RWM thickness, RWM diameter, and RWM surface area in humans and animals

From: Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans

Species

Central RWM thickness (µm)

RWM diameter (mm)

RWM surface area (mm2)

Reference

Human

69–70a

Long axis: 2.1

2.98 ± 0.43b

Sahni et al. [133]

Short axis: 1.8

Takahashi et al. [140]

Zhang and Gan [144]

Sheep

56–74a

Long axis: 2.3

3.79c

Han et al. [138]

Short axis: 2.1

Monkey (Rhesus macaque)

40–60

NA

NA

Goycoolea et al. [139]

Cat

20–40

1.5 – 2.0

1.77–3.14d

Goycoolea et al. [143]

Guinea pig

30–53

Long axis:1.3

1.18 ± 0.08b

Ghiz et al. [142]

Short axis: 0.9

Gan et al. [137]

Chinchilla

11–17a

Long axis:1.4

1.06 ± 0.23b

Schachern et al. [136]

Short axis: 1.0

Vrettakos et al. [141]

Rat

9–14a

NA

NA

Yoon and Hellstrom [135]

Mice

9–11a

NA

NA

Kitamura et al. [134]

  1. RWM: Round window membrane; NA: Not available
  2. aRange adapted from mean ± 1 standard deviation
  3. bData in mean ± standard deviation
  4. cCalculated from the diameter data with assumption of the RWM is in shape of a ellipse
  5. dCalculated from the diameter data with assumption of the RWM is in shape of a circle