Fig. 1
From: Insight into the emerging and common experimental in-vivo models of Alzheimer’s disease
Pathological similarities between human and rodent brain in AD. This figure shows the similarities in the pathologies of rodent brain and human brain during the progression of Alzheimer’s disease. There occurs accumulation of amyloid plaques and formation of tangles along with other hallmarks like neuroinflammation, oxidative stress and synaptic dysfunction. These similarities make the animals suitable for AD research which may aid in the development of potent therapeutics for AD