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Table 1 Escape latency data and TSQT data of compounds 28, 28ae

From: The memory ameliorating effects of novel N-benzyl pyridine-2-one derivatives on scopolamine-induced cognitive deficits in mice

Compound

Escape latency (s)

TSTQ (s)

1st day

2nd day

3rd day

4th day

5th day

Control

79.14 ± 0.19

50 ± 0.15

33 ± 0.21

19.23 ± 0.22

9.15 ± 0.09

36.4 ± 0.22

Scp + vehicle

78.65 ± 0.82

80.64 ± 0.39

82.82 ± 0.37

84.15 ± 0.33

86.25 ± 0.33

18.55 ± 0.88

Scp + donepezil

80.65 ± 0.81

69.66 ± 0.39

31.15 ± 0.37

25.15 ± 0.33

11.25 ± 0.32

37.92 ± 0.68

Scp + 28

74.33 ± 0.41

55.16 ± 0.27

34.16 ± 0.25

15.5 ± 0.18

2.33 ± 0.47

46.48 ± 0.8

Scp + 28a

82.53 ± 0.98

41.33 ± 0.89

23.83 ± 0.19

16.66 ± 0.19

4.33 ± 0.74

40.44 ± 0.4

Scp + 28b

83.16 ± 0.21

41.66 ± 0.18

21.33 ± 0.12

15.33 ± 0.18

4.33 ± 0.25

44.44 ± 0.45

Scp + 28c

81.16 ± 0.16

55.66 ± 0.25

34.33 ± 0.17

12.0 ± 0.23

5.00 ± 0.18

40.00 ± 0.58

Scp + 28d

82.00 ± 0.30

43.33 ± 0.29

26.83 ± 0.24

13.0 ± 0.25

3.83 ± 0.13

45.25 ± 0.60

Scp + 28e

85.0 ± 0.32

52.83 ± 0.18

27.33 ± 0.19

16.66 ± 0.16

4.0 ± 0.11

44.56 ± 0.44