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Table 4 Effects of naringin on reproductive hormones

From: Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining redox balance

 

CTRL

DMU

DM + naringin

DM + OPE

DM + Met

GnRH(mIU/mL)

11.32 ± 0.61

4.23 ± 0.31a

6.12.4 ± 0.31a,b

7.29 ± 0.29a,b,c

7.31 ± 0.52a,b,c

FSH (mIU/ml)

3.98 ± 0.23

1.93 ± 0.20a

2.32 ± 0.43a,b

2.99 ± 0.32a,b,c

2.96 ± 0.39a,b,c,

LH (mIU/ml)

6.94 ± 0.24

1.52 ± 0.32a

4.07 ± 0.35a,b

5.43 ± 0.45a,b,c

5.55 ± 0.45a,b,c

Testosterone (ng/ml)

3.66 ± 0.31

0.75 ± 0.25a

1.34 ± 0.34a,b

1.57 ± 0.31a,b,c

1.56 ± 0.21a,b,c

Estradiol (pg/ml)

0.57 ± 0.13

2.64 ± 0.23a

0.61 ± 0.25b

0.60 ± 0.32b

0.59 ± 0.36b

Prolactin (ng/ml)

0.83 ± 0.21

3.15 ± 0.36a

0.82 ± 0.16b

0.82 ± 0.21b

0.81 ± 0.27b

  1. Data were analyzed by one way ANOVA (and expressed as mean ± SEM) followed Tukey’s posthoc test. DMU: Diabetic untreated, DM + naringin: Diabetic treated with naringin; DM + OPE: Diabetic treated with orange peel extract; DM + met: Diabetic, treated with metformin
  2. aP < 0.05 vs control
  3. bP < 0.05 vs DMU
  4. cP < 0.05 vs DM + naringin
  5. dP < 0.05 vs DM + OPE