Fig. 3
From: Morin ameliorates myocardial injury in diabetic rats via modulation of inflammatory pathways
Effect of morin on biochemical parameters, cardiac-injury markers, and Pathological changes A.MDA (Malonaldehyde) levels in nM per gram heart tissue weight. B. GSK (Reduced glutathione) levels in µg present per gram of rat heart tissue weight. C. SOD (superoxide dismutase) levels in the Unit of SOD present per gram of heart tissue weight. D. LDH (Lactate dehydrogenase) and CK-MB (Creatine Kinase-MB) levels in rat serum in Units present per liter of serum. Statistical analysis was performed using one-way ANOVA followed by Bonferroni multiple comparison tests. All values are expressed as mean ± SEM (n = 6). Error bars with different superscripts are shown as significantly different (P < 0.05) where “*” indicates statistical difference between N vs DC; “#” specify the difference between DC vs D + I and D + M; however “$” shows statistical difference in between D + I vs D + I + M). N: Normal; DC: Diabetes control; D + I: Diabetes + Isoproterenol (ISO); D + I + M: Diabetes + ISO + Morin 40 mg/kg; D + M: Diabetes + Morin 40 mg/kg. E. Effect of morin on histopathological changes in rat models of diabetes and myocardial injury (200x; scale bar 100 μm; n = 3). Arrow represents the myocardial damage as infiltration of immune cells, myocardial membrane damage, and necrosis. a. Normal; b. Diabetes control; c. Diabetes + Isoproterenol (ISO); d. Diabetes + ISO + Morin 40 mg/kg; e. Diabetes + Morin 40 mg/kg