Fig. 5
From: Morin ameliorates myocardial injury in diabetic rats via modulation of inflammatory pathways
Effect of Morin on MAPK and inflammatory pathway proteins A.Representative western blots and their densitometric quantification w.r.t. respective loading control. Bars represent the relative intensity of respective protein normalized with Normal group. a. MAPK-ERK/ P-ERK. b. P38/ P-P38. c. JNK/ P-JNK. d. NF-κBp65/ P- NF-κBp65. e. IKKβ/ P-IKKβ. B. Concentration of inflammatory cytokines TNF and IL-6 estimated through ELISA following manufacturer’s protocol. C. Concentration of inflammasome proteins Caspase-1, NLRP-3 and IL-1β proteins. Statistical analysis was performed using one-way ANOVA followed by Bonferroni multiple comparison tests (n = 3). Error bars with different superscripts are shown as significantly different (P < 0.05) where “*” indicates statistical difference between N vs DC; “#” specify the difference between DC vs D + I and D + M; however “$” shows statistical difference in between D + I vs D + I + M). N: Normal; DC: Diabetes control; D + I: Diabetes + Isoproterenol (ISO); D + I + M: Diabetes + ISO + Morin 40 mg/kg; D + M: Diabetes + Morin 40 mg/kg