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Table 3 Renal, liver, and metabolic marker evaluation in acute toxicity study

From: In silico, anti-inflammatory and acute toxicological evaluation of an indigenous medicinal plant Pterospermum rubiginosum using Sprague-Dawley rats

Parameters

Group I

Group II

Group III

Group IV

Group V

Renal markers in serum

Urea (U/L)

40.49 ± 2.79

41.44 ± 2.89

42.78 ± 4.29

42.28 ± 3.06

44.71 ± 2.66

Creatinine (mg/dL)

0.56 ± 0.07

0.55 ± 0.08

0.58 ± 0.04

0.58 ± 0.05

0.61 ± 0.04

Uric acid (mg/dL)

0.96 ± 0.35

0.93 ± 0.47

1.10 ± 0.45

1.01 ± 0.38

1.16 ± 0.40

Liver marker in serum

SGOT (U/L)

69.79 ± 4.48

69.86 ± 6.10

71.11 ± 5.88

73.47 ± 5.78

77.47 ± 6.90

SGPT (U/L)

20.15 ± 3.56

22.10 ± 4.40

23.51 ± 4.84

24.03 ± 4.04

26.72 ± 3.30

TP (g/dL)

5.93 ± 0.41

5.99 ± 0.30

5.96 ± 0.45

6.20 ± 0.42

6.12 ± 0.57

Albumin (g/dL)

3.03 ± 0.61

3.33 ± 0.56

3.40 ± 0.52

3.47 ± 0.53

3.34 ± 0.58

Metabolic serum markers

Triglycerides (mg/dl)

42.60 ± 5.44

45.30 ± 6.05

48.57 ± 7.67

50.18 ± 6.38

51.82 ± 4.97

TC (mg/dl)

52.52 ± 5.10

59.58 ± 5.18

62.09 ± 7.50

63.16 ± 4.94

68.18 ± 4.90

  1. Values are expressed as mean ± standard deviation (n = 6, and P < 0.05); Units per litre: U/L; milligram /decilitre: mg/dL; gram/deciliter: g/dL; serum glutamic-oxaloacetic transaminase: SGOT; Serum Glutamic Pyruvic Transaminase: SGPT; Total protein: TP; Total cholesterol: TC