In silico, anti-inflammatory and acute toxicological evaluation of an indigenous medicinal plant Pterospermum rubiginosum using Sprague-Dawley rats

Table 4 Antioxidant marker and lipid peroxidation product evaluation in acute toxicity study

Parameters	Group I	Group II	Group III	Group IV	Group V
Antioxidant marker study in liver cells
GPx (mM/dl)	31.90 ± 2.02	33.00 ± 2.72	34.38 ± 2.12	34.80 ± 2.02	33.60 ± 2.09
GSH (mM/dl)	81.07 ± 3.03	83.00 ± 2.99	83.15 ± 3.44	84.02 ± 3.02	83.45 ± 2.52
GRd (mM/dl)	144.17 ± 5.20	143.11 ± 4.04	147.04 ± 5.21	145.40 ± 4.75	143.22 ± 4.12
SOD (U/dl)	2.45 ± 0.26	2.61 ± 0.31	2.55 ± 0.21	2.59 ± 0.54	2.90 ± 0.44
Catalase (mM/min/mg)	7.12 ± 0.45	7.57 ± 0.50	7.55 ± 0.46	7.47 ± 0.53	7.70 ± 0.43
Lipid peroxidation products in liver cells
MDA (mM/dl)	2.56 ± 0.36	2.54 ± 0.26	2.58 ± 0.32	2.60 ± 0.36	2.71 ± 0.31
CD (mM/dl)	5.65 ± 0.39	5.54 ± 0.29	5.60 ± 0.44	5.54 ± 0.31	5.51 ± 0.34
HP(mM/dl)	7.95 ± 0.44	7.57 ± 0.27	7.64 ± 0.40	7.73 ± 0.43	7.90 ± 0.49

Values are expressed as mean ± standard deviation (n = 6). millimoles per decilitre: mM/dl; Units per decilitre: U/dl; millimolar per mins per milligram: mM/min/mg; millimoles per decilitre: mM/dl; Glutathione peroxidise: GPx, Reduced glutathione: GSH; Glutathione reductase: GRd; Sodium dismutase: SOD; Malonaldehyde: MDA; Conjugated dienes: CD; Hydroperoxides: HP

ISSN: 2233-7660