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Anti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella

Laboratory Animal Research volume 34, pages 44–47 (2018)Cite this article

Abstract

Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria (E.) tenella. This experiment was performed on the 3-day-old chicks (n=30). The animals were divided with 3 groups; TFE 15mg per animal+infected (n=10), TTE untreated+infected (n=10) and non-infected control (n=10). Animals were administrated with or without TTE during 1 week, and then inoculated with E. tenella. The anti-coccidial activity were evaluated with oocysts shedding numbers in stools, body weights changes and food intake changes. The TTE-inoclated animals revealed significantly decreased stool oocysts numbers (P<0.05) when compared to the TTE untreated animals. Also, TTE-treated animals showed more increased body weight gains (P<0.05) than the TTE untreated animals. These results demonstrate that TTE produce anticoccidial activities against E. tenella. TTE could be a promising treatment for the coccidiosis.

References

  1. Dalloul RA, Lillehoj HS. Poultry coccidiosis: recent advancements in control measures and vaccine development. Expert Rev Vaccines 2006; 5(1): 143–163.

    Article  CAS  Google Scholar 

  2. Williams RB. Relative virulences of a drug-resistant and a drug- sensitive strain of Eimeria acervulina, a coccidium of chickens. Vet Parasitol 2006; 135(1): 15–23.

    Article  CAS  Google Scholar 

  3. Kaingu F, Liu D, Wang L, Tao J, Waihenya R, Kutima H. Anticoccidial effects of Aloe secundiflora leaf extract against Eimeria tenella in broiler chicken. Trop Anim Health Prod 2017; 49(4): 823–828.

    Article  Google Scholar 

  4. Zhang JD, Xu Z, Cao YB, Chen HS, Yan L, An MM, Gao PH, Wang Y, Jia XM, Jiang YY. Antifungal activities and action mechanisms of compounds from Tribulus terrestris L. J Ethnopharmacol 2006; 103(1): 76–84.

    Article  CAS  Google Scholar 

  5. Chhatre S, Nesari T, Somani G, Kanchan D, Sathaye S. Phytopharmacological overview of Tribulus terrestris. Pharmacogn Rev 2014; 8(15): 45–51.

    Article  Google Scholar 

  6. Borran M, Minaiyan M, Zolfaghari B, Mahzouni P. Protective effect of Tribulus terrestris fruit extract on cerulein-induced acute pancreatitis in mice. Avicenna J Phytomed. 2017; 7(3): 250–260.

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Hammoda HM, Ghazy NM, Harraz FM, Radwan MM, ElSohly MA, Abdallah II. Chemical constituents from Tribulus terrestris and screening of their antioxidant activity. Phytochemistry 2013; 92: 153–159.

    Article  CAS  Google Scholar 

  8. Al-Bayati FA, Al-Mola HF. Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq. J Zhejiang Univ Sci B. 2008; 9(2): 154–159.

    Article  Google Scholar 

  9. Dinchev D, Janda B, Evstatieva L, Oleszek W, Aslani MR, Kostova I. Distribution of steroidal saponins in Tribulus terrestris from different geographical regions. Phytochemistry 2008; 69(1): 176–186.

    Article  CAS  Google Scholar 

  10. Lee HA, Hong S, Chung Y, Kim O. Sensitive and specific identification by polymerase chain reaction of Eimeria tenella and Eimeria maxima, important protozoan pathogens in laboratory avian facilities. Lab Anim Res 2011; 27(3): 255–258.

    Article  Google Scholar 

  11. Stotish RL, Wang CC, Meyenhofer M. Structure and composition of the oocyst wall of Eimeria tenella. J Parasitol 1978; 64(6): 1074–1081.

    Article  CAS  Google Scholar 

  12. Bourke CA, Stevens GR, Carriqan MJ. Locomotor effects in sheeps of alkaloids identified in Australian Tribulus terrestris. Aust Vet J 1992; 69(7): 163–165.

    Article  CAS  Google Scholar 

  13. Yan W, Ohtani K, Kasai R, Yamasaki K. Steroidal Saponins from Fruits of Tribulus terrestris. Phytochemistry 1996; 42(5): 1417–1422.

    Article  CAS  Google Scholar 

  14. Soleimanpour S, Sedighinia FS, Safipour Afshar A, Zarif R, Ghazvini K. Antibacterial activity of Tribulus terrestris and its synergistic effect with Capsella bursa-pastoris and Glycyrrhiza glabra against oral pathogens: an in-vitro study. Avicenna J Phytomed 2015; 5(3): 210–217.

    CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Center for Animal Resource Development, Wonkwang University, Iksan, Jeonbuk, Korea, 460 Iksandaero, 54538

    Sunhwa Hong, Mi-Na Moon, Eun-Kyung Im, Jum-Soon Won & Okjin Kim

  2. Technlogy Service Division, National Institute of Animal Science, Rural Development Administration, Wanju, Korea

    Ji-Hyun Yoo

  3. Institute of Animal Experiment & Evaluation, Animal Disease Research Unit, Wonkwang University, Iksan, Korea

    Okjin Kim

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  1. Sunhwa Hong
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  2. Mi-Na Moon
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  3. Eun-Kyung Im
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Correspondence to Okjin Kim.

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Hong, S., Moon, MN., Im, EK. et al. Anti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella. Lab Anim Res 34, 44–47 (2018). https://doi.org/10.5625/lar.2018.34.1.44

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  • DOI: https://doi.org/10.5625/lar.2018.34.1.44

Keywords

Laboratory Animal Research

ISSN: 2233-7660