- Letter
- Open Access
- Published:
Anti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella
Laboratory Animal Research volume 34, pages 44–47 (2018)
Abstract
Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria (E.) tenella. This experiment was performed on the 3-day-old chicks (n=30). The animals were divided with 3 groups; TFE 15mg per animal+infected (n=10), TTE untreated+infected (n=10) and non-infected control (n=10). Animals were administrated with or without TTE during 1 week, and then inoculated with E. tenella. The anti-coccidial activity were evaluated with oocysts shedding numbers in stools, body weights changes and food intake changes. The TTE-inoclated animals revealed significantly decreased stool oocysts numbers (P<0.05) when compared to the TTE untreated animals. Also, TTE-treated animals showed more increased body weight gains (P<0.05) than the TTE untreated animals. These results demonstrate that TTE produce anticoccidial activities against E. tenella. TTE could be a promising treatment for the coccidiosis.
References
Dalloul RA, Lillehoj HS. Poultry coccidiosis: recent advancements in control measures and vaccine development. Expert Rev Vaccines 2006; 5(1): 143–163.
Williams RB. Relative virulences of a drug-resistant and a drug- sensitive strain of Eimeria acervulina, a coccidium of chickens. Vet Parasitol 2006; 135(1): 15–23.
Kaingu F, Liu D, Wang L, Tao J, Waihenya R, Kutima H. Anticoccidial effects of Aloe secundiflora leaf extract against Eimeria tenella in broiler chicken. Trop Anim Health Prod 2017; 49(4): 823–828.
Zhang JD, Xu Z, Cao YB, Chen HS, Yan L, An MM, Gao PH, Wang Y, Jia XM, Jiang YY. Antifungal activities and action mechanisms of compounds from Tribulus terrestris L. J Ethnopharmacol 2006; 103(1): 76–84.
Chhatre S, Nesari T, Somani G, Kanchan D, Sathaye S. Phytopharmacological overview of Tribulus terrestris. Pharmacogn Rev 2014; 8(15): 45–51.
Borran M, Minaiyan M, Zolfaghari B, Mahzouni P. Protective effect of Tribulus terrestris fruit extract on cerulein-induced acute pancreatitis in mice. Avicenna J Phytomed. 2017; 7(3): 250–260.
Hammoda HM, Ghazy NM, Harraz FM, Radwan MM, ElSohly MA, Abdallah II. Chemical constituents from Tribulus terrestris and screening of their antioxidant activity. Phytochemistry 2013; 92: 153–159.
Al-Bayati FA, Al-Mola HF. Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq. J Zhejiang Univ Sci B. 2008; 9(2): 154–159.
Dinchev D, Janda B, Evstatieva L, Oleszek W, Aslani MR, Kostova I. Distribution of steroidal saponins in Tribulus terrestris from different geographical regions. Phytochemistry 2008; 69(1): 176–186.
Lee HA, Hong S, Chung Y, Kim O. Sensitive and specific identification by polymerase chain reaction of Eimeria tenella and Eimeria maxima, important protozoan pathogens in laboratory avian facilities. Lab Anim Res 2011; 27(3): 255–258.
Stotish RL, Wang CC, Meyenhofer M. Structure and composition of the oocyst wall of Eimeria tenella. J Parasitol 1978; 64(6): 1074–1081.
Bourke CA, Stevens GR, Carriqan MJ. Locomotor effects in sheeps of alkaloids identified in Australian Tribulus terrestris. Aust Vet J 1992; 69(7): 163–165.
Yan W, Ohtani K, Kasai R, Yamasaki K. Steroidal Saponins from Fruits of Tribulus terrestris. Phytochemistry 1996; 42(5): 1417–1422.
Soleimanpour S, Sedighinia FS, Safipour Afshar A, Zarif R, Ghazvini K. Antibacterial activity of Tribulus terrestris and its synergistic effect with Capsella bursa-pastoris and Glycyrrhiza glabra against oral pathogens: an in-vitro study. Avicenna J Phytomed 2015; 5(3): 210–217.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://doi.org/creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Hong, S., Moon, MN., Im, EK. et al. Anti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella. Lab Anim Res 34, 44–47 (2018). https://doi.org/10.5625/lar.2018.34.1.44
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.5625/lar.2018.34.1.44
Keywords
- Coccidiosis
- Eimeria
- antiprotozoal
- Tribuli fructus
- Tribulus terrestris