About the editors

Sung-Dae Cho is a professor at School of Dentistry, Seoul National University, in Seoul, South Korea. Sung-Dae and his laboratory focus on Identification of molecular targets and signaling pathways related to apoptosis and metastasis in oral cancer and developments of natural product-derived anticancer drugs. (ORCID 0000-0001-8670-9579)

Jae-Hoon Choi is a professor at the department of life science, college of natural sciences, Hanyang University in Seoul, South Korea.  His laboratory is focusing on understanding the function of innate immune cells including dendritic cells and macrophages in inflammatory cardiovascular diseases using mouse models, and also studying about the interactions between immune and non-immune cells during the normal and pathological conditions of cardiovascular systems. (ORCID 0000-0002-5265-3463)

Sungsoon Fang is a Professor at Severance Biomedical Science Institute, Yonsei University College of Medicine in Seoul, South Korea. Sungsoon and his laboratory focus on the mechanisms of how hormonal signaling pathways that control energy intake and expenditure maintain physiological homeostasis using animal system. His goal aims to identify pharmaceutical targets that reduce energy intake and/or increase energy expenditure to develop novel drug discovery for the treatment of chronic metabolic syndromes including obesity and diabetes. (ORCID 0000-0003-0201-5567)

Jung Joo Hong is an associate professor at the University of Science & Technology, and the principal researcher at Korea Research Institute of Bioscience and Biotechnology (KRIBB), South Korea. Jung Joo Hong earned a Ph.D from the University of Minnesota and had the opportunity to join the Division of Microbiology, Pathology, and immunology at the Yerkes National Primate Research Center at Emory University as a postdoctoral fellow. Jung Joo Hong and his lab focus on the development of non-human primate model for human infectious diseases. Our ultimate goal is to use this model to determine the efficacy of a vaccine platform or therapy in an NHP model prior to clinical testing, while simultaneously understanding the mechanisms of host-pathogen interactions. (ORCID 0000-0002-9795-6513) 

In Koo Hwang is a professor at the Seoul National University College of Veterinary Medicine in Seoul, South Korea. In Koo and his laboratory focus on brain ischemia, metabolic diseases, and aging in relation to adult hippocampal neurogenesis. Morphological evidences in most biological studies are used to give the conceiving evidences to the research. In Koo has been Editor of Laboratory Animal Research since 2017. (ORCID 0000-0002-0533-4638)

Kyoungmi Kim is an associate professor at the Department of Physiology, Korea University College of Medicine in Seoul, South Korea. Kyoungmi and her laboratory focus on improvement of genome editing tools based on the CRISPR system. As well as, she is studying the development of human disease mouse model using engineered genome editing tools. Her goal is aimed at the development and therapeutic research of mouse models of human diseases using newly developed gene editing tools. (ORCID 0000-0003-0941-806X)

Hyuk Wan Ko is an associate professor at the Dept. of Biochemistry, Yonsei University in Seoul, South Korea. His laboratory focus on unveiling the molecular mechanism of mammalian specific Hedgehog signaling and role of primary cilia in mouse development and disease. Using the mouse genetic model system, his goal aims to understand the molecular basis of primary cilia related Hedgehog signaling. He further pursues to reveal the pathogenesis of human genetic disorders, ciliopathies, which are caused by defects in cilia structure or function. (ORCID 0000-0003-1753-1900 )

Daekee Lee has long experience in the development of transgenic mice and genetically targeted mice, and has been trained in mouse genetics. A study on the effect of the EGFR signaling system on cell proliferation and death was conducted using a colon cancer model, and new genes related to metastasis and their functions are being studied at the cell and mouse level. (ORCID 0000-0001-8130-2059)

Ho Lee is a professor and chair at the Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, South Korea. Ho Lee has a Ph.D in Biochemistry at the Seoul National University and has performed post-doctoral research in Mouse Genetics at the KAIST (Daejeon, Korea).

Ho Lee and his laboratory focus on in vivo functional analysis of tumor-related genes using mouse models such as Kras lung and pancreatic, MMTV-Her2 breast, and APC colon cancer models. Based on the integrated approach with molecular biology, genetics, and oncology, his research aims to understand in vivo function of tumor-related genes and validate them as anti-cancer drug targets.

He and his laboratory are also involved in drug development process. Using mouse models as a preclinical platform, they uncovered the mechanism of action (MoA) and performed proof of concept (PoC) studies of drug candidates. (ORCID 0000-0001-5573-742x)

Jeong-Soo Lee is the principal investigator at Microbiome Convergence Research center in KRIBB, Daejeon in Korea. Dr. JS Lee and lab memebers are interested in roles of the gut microbiome in intestinal inflammatory disorders such as IBD and neurological disorders including autism spectrum disorders and tauopathy of the host. Dr. Lee's lab utilizes zebrafish as a primary animal model to unravel the interaction of the microbiome and the host, by generating new disease models and developing techniques for gene expression and germfree conditions, combined with high resolution in vivo  imaging for cellular behaviors. (ORCID 0000-0002-8491-4429)

Keunwook Lee is an associate professor at the Department of Biomedical Science, Hallym University in South Korea. Keunwook and his laboratory focus on the mechanism into how cellular signaling network controls immunological functions to shape the immune microenvironment within the inflamed tissues. Using the mouse genetic models and ex vivo cultivation system, his goal aims to understand the molecular basis of PI3K-PTEN-mTOR signaling networks in the immune compartments in relation to inflammatory diseases and cancer. (ORCID 0000-0002-4713-8547) 

Joo Young Lee is a professor at College of Pharmacy, the Catholic University of Korea in South Korea. Joo Young and her laboratory focus on the regulation of immune system and the toxicological action of chemicals in the development of chronic diseases including metabolic diseases, atopic dermatitis, and cancer. With both cell system-based technology and animal disease models, the research goals are to elucidate the biological mechanism of host defense against toxic chemicals, invading pathogens, and danger signals and to provide effective strategies to prevent the development of chronic diseases. Joo Young has published over 100 international papers and served as editorial board members of reputed journals. (ORCID 0000-0002-6020-3040)  

Changjong Moon is a Professor at the Department of Veterinary Anatomy, College of Veterinary Medicine, Chonnam National University in Gwangju, South Korea. The goal of his laboratory is to understand the function of various signal transduction pathways in the hippocampus and the relationship between hippocampal neurogenesis and brain dysfunctions. He use molecular, cellular, histological, and behavioral approaches to identify the molecular components involved in brain functions, including cognition and emotional regulation. (ORCID 0000-0003-2451-0374)

Jong-Hwan Park is a professor at Laboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University in Gwangju, South Korea. Jong-Hwan Park and his lab focus on host innate immune responses based on pattern recognition receptors against microbial infections. He has published over 100 international papers and served as editorial board members of reputed immunology journals. (ORCID 0000-0003-4664-5640)

Man-Seong Park is a professor at the Department of Microbiology, and a director of the Biosafety Center, Korea University School of Medicine in Seoul, South Korea. Dr. Park got a Ph.D. in Microbiology, Korea University and has performed post-doctoral research in Microbiology at the Icahn School of Medicine at Mount Sinai, New York. He has researched on molecular virology, vaccine and anti-viral drug development of negative-strand RNA viruses including influenza virus, MERS-CoV, Zika virus, Newcastle disease virus, dengue virus, and Hantavirus. He has been the Managing Editor of PLoS One since 2009. (ORCID 0000-0002-7427-486X)

Jun Gyo Suh is a professor of the Department of Medical Genetics, College of Medicine, Hallym University, South Korea. Jun Gyo Suh and his lab focus on understanding genetic analysis of inbred mice originated from Korean wild mice and functional research of deafness related genes using animal models. (ORCID 0000-0001-9143-6755) 

Young Hoon Sung has an expertise in generating genetic mouse models using CRISPR-Cas systems, and his laboratory is focusing to develop diverse sequence-humanized mouse models harboring mutant human sequences identified in human patients, especially for the rare genetic disorders. He is planning to use his mouse models not only for the translational researches of the diseases but also to prove the effectiveness of CRISPR-Cas system as a drug. (ORCID 0000-0002-1508-9883)

Sang Sun Yoon is a professor at the Department of Microbiology and Immunology, Yonsei University College of Medicine in Seoul, Korea.

Sang Sun and his lab members are interested in infection biology, focusing on bacterial pathogenesis and host-microbe interaction. Lately, his lab also became interested in elucidating effects of microbiome on human biology. Sang Sun characterized several commensal microbes with potential to cure diverse human diseases and microbiome-derived genes that lead to the production of useful metabolites. Sang Sun has published over 60 papers and served as editors in many journals. (ORCID 0000-0003-2979-365X)

Hye-Jin Boo is an assistant professor at the Department of Histology, Jeju National University College of Medicine in Jeju, South Korea. Hye-Jin and her laboratory focus on defining the pathophysiological mechanisms that affect tissue injury and the interaction of organ systems in chronic inflammatory diseases. Her research aims to understand the pathogenesis of chronic inflammatory diseases and define therapeutic targets for their treatment, utilizing genetically engineered or disease-specific mouse models, ex vivo culture systems, and cutting-edge techniques. (ORCID: 0000-0002-9700-5443)
 

Joohee Jung is a professor at College of Pharmacy, Duksung Women’s University in South Korea. She and her laboratory focus on the anticancer effect of natural products via GPER signaling in various xenograft models (gastrointestinal cancer-derived organoid xenograft model, patient-derived xenograft model, spontaneous metastasis model, etc.). Additionally, she is interested in developing an AI-based platform for chemical hazards prediction/assessment. She served as editorial board members of reputed journals. (ORCID 0000-0001-9124-9052)
 

Wonhyo Seo is an assistant professor in the College of Pharmacy, Ewha Womans University, and is conducting research on the pathogenesis of acute/chronic liver diseases caused by various factors (i.e., alcohol, high fat diet, and toxicants).

Wonhyo Seo received a Ph.D degree from the Graduate School of Medical Sciences at the Korea Advanced Institute of Science and Technology (KAIST). Wonhyo has published in a number of renowned international academic journals, including Hepatology, Cellular and Molecular Gastroenterology and Hepatology, and Journal of Hepatology.

Wonhyo and his research team mainly focus on the involvement of hepatocyte derived-extracellular vesicles in the progression of liver diseases, and how to promote liver disease through interaction with non-parenchymal cells and hepatocytes. (ORCID 0000-0002-2610-951X)

Jongki Cho is a professor at the College of Veterinary Medicine, Chungnam National University, in Daejeon, South Korea. His laboratory focuses on the generation of transgenic pigs for xenotransplantation and human disease-model animals, stem cells, animal reproduction, and related disorders. Recently, they have been studying the roles of exosomes in reproduction, including ovulation, fertilization, implantation, parturition, and uterine endometrial organoids. (ORCID 0000-0002-8431-0457)

Jeong Ho Hwang is a Principle Investigator of Korea Institute of Toxicology and Associate Professor at the University of Science & Technology. His laboratory focuses on the immunology based on pig to Non-human primate xenotransplantation and Establishment of large animal model baring human disease based on toxicology. Recently, they have been studying the efficacy and safety of new drugs and indentifying the mechanism of actions of test item using animal models.(ORCID 0000-0002-4763-8373)