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  1. This study was performed to investigate the effect of a concentrate of fermented wild ginseng root culture (HLJC0701) on memory improvement in the scopolamine (SPL)-induced memory-deficient mouse model. Eight-...

    Authors: Song-Hee Han, Sung-June Kim, Young Won Yun, Sang Yoon Nam, Hu-Jang Lee and Beom-Jun Lee
    Citation: Laboratory Animal Research 2018 34:3101037
    Content type: OriginalPaper Published on:

  2. This study investigated the anti-cancer potential of a near-infrared fluorescence (NIRF) molecule conjugated with Cetuximab (Cetuximab-NIRF) in six-week-old female BALB/c athymic (nu+/nu+) nude mice. A431 cell...

    Authors: Ji Young Yun, Byung-Hwa Hyun, Sang Yoon Nam, Young Won Yun, Hu-Jang Lee and Beom-Jun Lee
    Citation: Laboratory Animal Research 2018 34:3101030
    Content type: OriginalPaper Published on:

  3. C57BL/6N mice are inbred strains widely used in biomedical research. Hence, a large amount of basic data has been accumulated. However, in the field of histopathology, spontaneous data for relatively younger m...

    Authors: Do-Yong Park, Byoung-Seok Lee, Woo-Jin Kim, Wan-Jung Im, Ji-Seok Han, Heejin Park, Mi-Jin Yang, Jae-Woo Cho, Da Hee Kim, Su-Cheol Han, Yong-Bum Kim and Hwa-Young Son
    Citation: Laboratory Animal Research 2018 34:3101020
    Content type: OriginalPaper Published on:

  4. The aim of this study is to evaluate the reporting quality of animal experiments in Korea using the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guideline developed in 2010 to overcome the reproduc...

    Authors: Mi-Hyun Nam, Myung-Sun Chun, Je-Kyung Seong and Hoon-Gi Kim
    Citation: Laboratory Animal Research 2018 34:3101011
    Content type: OriginalPaper Published on:

  5. Chronic obstructive pulmonary disease (COPD) was the 3rd leading cause of death in 2012 worldwide. It is particularly severe in the elderly, who are at risk of death by coughing, mucous hypersecretion, and finall...

    Authors: Soon-Young Lee, Jin-Ho Cho, Seung Sik Cho, Chun-Sik Bae, Gye-Yeop Kim and Dae-Hun Park
    Citation: Laboratory Animal Research 2018 34:3101001
    Content type: OriginalPaper Published on:

  6. Quercetin, a natural flavonoid, copiously exists in vegetable, fruits and tea. Quercetin is beneficial to neurodegenerative disorders via its strong anti-oxidant and anti-inflammatory activities. γ-Enolase is ...

    Authors: Seong-Jun Jeon, Myeong-Ok Kim, Fawad Ali-Shah and Phil-Ok Koh
    Citation: Laboratory Animal Research 2018 33:3304308
    Content type: OriginalPaper Published on:

  7. A correlation between endoplasmic reticulum (ER) stress and laxative effects was first reported in a constipation model treated with an aqueous extract of Liriope platyphylla (AEtLP) roots. To investigate the cor...

    Authors: Ji Eun Kim, Bo Ram Song, Woo Bin Yun, Jun Young Choi, Jin Ju Park, Mi Rim Lee and Dae Youn Hwang
    Citation: Laboratory Animal Research 2018 33:3304298
    Content type: OriginalPaper Published on:

  8. Thread-embedding therapy has been widely applied for cosmetic purposes such as wrinkle reduction and skin tightening. Particularly, gold thread was reported to support connective tissue regeneration, but, its ...

    Authors: Jong-Hwan Kim, Eun-Young Cho, Euna Kwon, Woo-Ho Kim, Jin-Sung Park, Yong-Soon Lee, Jun-Won Yun and Byeong-Cheol Kang
    Citation: Laboratory Animal Research 2018 33:3304291
    Content type: OriginalPaper Published on:

  9. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Woo Bin Yun, Hye Ryeong Kim, Ji Eun Kim, Jun Young Choi, Mi Rim Lee, Jin Ju Park, Bo Ram Song, Young Suk Jung, Hyun Keun Song, Joon Young Cho, Kil Soo Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3304321
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art18

  10. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Ji Eun Kim, Jung Hoon Nam, Joon Young Cho, Kil Soo Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3304320
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art17

  11. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Sou Hyun Kim, Keuk-Jun Kim, Joung-Hee Kim, Jae-Hwan Kwak, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim and Young-Suk Jung
    Citation: Laboratory Animal Research 2017 33:3304319
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art16

  12. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Sou Hyun Kim, Yong Lim, Ju Bin Park, Jae-Hwan Kwak, Keuk-Jun Kim, Joung-Hee Kim, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim and Young-Suk Jung
    Citation: Laboratory Animal Research 2017 33:3304318
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art15

  13. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Dong-Ju Hwang, Hyun-Keun Song, Kil-Soo Kim, Young-Suk Jung, Dae-Youn Hwang and Joon Young Cho
    Citation: Laboratory Animal Research 2017 33:3304317
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art13

  14. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Hye Ryeong Kim, Jun Young Choi, Kil Soo Kim, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2017 33:3304316
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art12

  15. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Jun Young Choi, Hye Ryeong Kim, Kil Soo Kim, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2017 33:3304315
    Content type: Erratum Published on:

    The original article was published in Laboratory Animal Research 2017 33:Art11

  16. In the present study, we examined the effects of Dendropanax morbifera Léveille leaf extract (DML) on dgalactose-induced morphological changes in microglia and cytokines, including pro-inflammatory cytokines (int...

    Authors: Kwon Young Lee, Hyo Young Jung, Dae Young Yoo, Woosuk Kim, Jong Whi Kim, Hyun Jung Kwon, Dae Won Kim, Yeo Sung Yoon, In Koo Hwang and Jung Hoon Choi
    Citation: Laboratory Animal Research 2017 33:3304283
    Content type: OriginalPaper Published on:

  17. This paper reports a case of super pregnancy in a BALB/c mouse pregnant with 30 pups following induction of superovulation using a PMSG-hCG protocol. Superovulation was induced in 10 mice by injecting 5 IU PMS...

    Authors: Hanieh Vaseghi, Asghar Mogheiseh, Masood Sepehrimanesh, Mojtaba Kafi and Mohammad Hossein Nooranizadeh
    Citation: Laboratory Animal Research 2017 33:3303280
    Content type: Case Report Published on:

  18. Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts...

    Authors: Mi Rim Lee, Ji Eun Kim, Woo Bin Yun, Jun Young Choi, Jin Ju Park, Hye Ryeong Kim, Bo Ram Song, Young Whan Choi, Kyung Mi Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3303270
    Content type: OriginalPaper Published on:

  19. Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly us...

    Authors: Tai-Young Hur, Seung-Hoon Lee, Sun-A Ock, Hyuk Song, Hyun-Jung Park, Ran Lee, Si-Heung Sung, Hyunjhung Jhun and Won-Young Lee
    Citation: Laboratory Animal Research 2017 33:3303264
    Content type: OriginalPaper Published on:

  21. Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intak...

    Authors: So-Hyeon Bok, Seung Sik Cho, Chun-Sik Bae, Dae-Hun Park and Kyung-Mok Park
    Citation: Laboratory Animal Research 2017 33:3303251
    Content type: OriginalPaper Published on:

  23. Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (...

    Authors: Ji Hyeon Ahn, Tae-Kyeong Lee, Joon Ha Park, Jeong Hwi Cho, In Hye Kim, Jae Chul Lee, Seongkweon Hong, Yong Hwan Jeon, Il Jun Kang, Young Joo Lee, Moo-Ho Won and Choong-Hyun Lee
    Citation: Laboratory Animal Research 2017 33:3303237
    Content type: OriginalPaper Published on:

  24. Among three representative species of Angelica found in Asian countries, including Korea, China, and Japan, Angelica acutiloba (AA) has been used as traditional herbal medicine with antitumor, antiinflammatory, a...

    Authors: Jun-Won Yun, Yun-Soon Kim, Euna Kwon, Seung-Hyun Kim, Ji-Ran You, Hyeon Hoe Kim, Jeong-Hwan Che and Byeong-Cheol Kang
    Citation: Laboratory Animal Research 2017 33:3303231
    Content type: OriginalPaper Published on:

  25. Angelica acutiloba (AA), a Japanese species of Danggui, has been used worldwide as a traditional herbal medicine with several bioactivities including anti-diabetic, anti-allergic, anti-inflammatory, anti-tumor, a...

    Authors: Jun-Won Yun, Euna Kwon, Seung-Hyun Kim, Ji-Ran You, Yun-Soon Kim, In Ae Park, Hyeon Hoe Kim, Jeong-Hwan Che and Byeong-Cheol Kang
    Citation: Laboratory Animal Research 2017 33:3303223
    Content type: OriginalPaper Published on:

  26. This study aims to evaluate early changes in retinal structure and BMP2 expression in the retina and crystalline lens by comparing streptozotocin-induced diabetic pigs and normal control group pigs.

    Authors: Jae Seung Jeong, Woon-Kyu Lee, Yeon Sung Moon and Na Rae Kim
    Citation: Laboratory Animal Research 2017 33:3303216
    Content type: OriginalPaper Published on:

  27. Artemisia argyi is used as a health supplement, tea, and food source in Korea. This study aimed to evaluate the effect of Artemisia argyi (AA) and its active compound, dehydromatricarin A (DA), on the attenuation...

    Authors: Na-Rae Shin, Sung-Hyeuk Park, Je-Won Ko, Hyung-Won Ryu, Seong-Hun Jeong, Jong-Choon Kim, Dong-Ho Shin, Hoon-Sang Lee and In-Sik Shin
    Citation: Laboratory Animal Research 2017 33:3303209
    Content type: OriginalPaper Published on:

  29. Pet turtles are well-known to harbor an array of bacterial pathogens which can cause zoonotic infections in humans as well as opportunistic infections in the turtles itself. Essential oils are the natural plan...

    Authors: Sabrina Hossain, Honghoi Heo, B. C. J. De Silva, S. H. M. P. Wimalasena, H. N. K. S. Pathirana and Gang-Joon Heo
    Citation: Laboratory Animal Research 2017 33:3303195
    Content type: OriginalPaper Published on:

  30. Korl:ICR mice, established by the Korean National Institute of Food and Drug Safety Evaluation (NIFDS), are characterized based on their genetic variation, response to gastric injury, and response to constipat...

    Authors: Ji Eun Sung, Ji Eun Kim, Hyun Ah Lee, Woo Bin Yun, Jun Young Choi, Mi Rim Lee, Jin Ju Park, Hye Ryeong Kim, Bo Ram Song, Young Suk Jung, Kil Soo Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3302187
    Content type: OriginalPaper Published on:

  31. C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neu...

    Authors: Woo Bin Yun, Hye Ryeong Kim, Ji Eun Kim, Jun Young Choi, Mi Rim Lee, Jin Ju Park, Bo Ram Song, Young Suk Jung, Hyun Keun Song, Joon Young Cho, Kil Soo Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3302179
    Content type: OriginalPaper Published on:

  32. Institute of Cancer Research (ICR) mice have been widely used in various research fields including toxicology, oncology, pharmacology, and pharmaceutical product safety testing for decades. However, annual ten...

    Authors: Ji Eun Kim, Jung Hoon Nam, Joon Young Cho, Kil Soo Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3302171
    Content type: OriginalPaper Published on:

  33. Doxorubicin is a widely used chemotherapeutic agents and is now part of standard therapeutic regimens for a variety of cancers (eg, hematopoietic malignancies and advanced solid tumors of the breast, ovary, th...

    Authors: Sou Hyun Kim, Keuk-Jun Kim, Joung-Hee Kim, Jae-Hwan Kwak, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim and Young-Suk Jung
    Citation: Laboratory Animal Research 2017 33:3302165
    Content type: OriginalPaper Published on:

  34. Non-alcoholic fatty liver disease (NAFLD) is believed to be the most prevalent liver disease worldwide and a major cause of chronic liver injury. It is characterized by lipid accumulation in the absence of sig...

    Authors: Sou Hyun Kim, Yong Lim, Ju Bin Park, Jae-Hwan Kwak, Keuk-Jun Kim, Joung-Hee Kim, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim and Young-Suk Jung
    Citation: Laboratory Animal Research 2017 33:3302157
    Content type: OriginalPaper Published on:

  35. This study was conducted to compare the multiple low-dose streptozotocin (MLDS)-induced diabetic patterns of Korl:ICR, A:ICR, and B:ICR mice obtained from three different sources. Six-week-old male ICR mice we...

    Authors: Do Yeon Lee, Myeong Hwan Kim, Hye Rin Suh, Young Suk Jung, Dae Youn Hwang and Kil Soo Kim
    Citation: Laboratory Animal Research 2017 33:3302150
    Content type: OriginalPaper Published on:

  36. Animal model, as an indispensable tool for scientific purposes of biomedical researches and clinical application, is a commonly used in various researches. Regarding to this, it is necessary to establish the m...

    Authors: Dong-Ju Hwang, Hyun-Keun Song, Kil-Soo Kim, Young-Suk Jung, Dae-Youn Hwang and Joon Young Cho
    Citation: Laboratory Animal Research 2017 33:3302140
    Content type: OriginalPaper Published on:

  37. Adaptive immunity is a type of immune response mediated by T and B cells, and is important response for immune response amplification and memory. In this study, the adaptive immunologic properties of C57BL/6NK...

    Authors: Hye Ryeong Kim, Jun Young Choi, Kil Soo Kim, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2017 33:3302132
    Content type: OriginalPaper Published on:

  38. Inbred mice, a systematically developed homogeneous animal, have been developed to maintain experimental reproducibility and to minimize experimental variables in animal-based studies. In particular, C57BL/6 m...

    Authors: Jun Young Choi, Hye Ryeong Kim, Kil Soo Kim, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2017 33:3302124
    Content type: OriginalPaper Published on:

  39. Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new inbred lines are b...

    Authors: Hyun Keun Song and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3302119
    Content type: Review Published on:

  40. Glucose is essential for testicular function; the uptake of carbohydrate-derived glucose by cells is mediated by glucose transporters (GLUTs). In the present study, we investigated the activity of GLUT1 and GL...

    Authors: Kyu Ri Hahn, Hyo Young Jung, Dae Young Yoo, Jong Whi Kim, Yang Hee Kim, Young Kwang Jo, Geon A. Kim, Jin Young Chung, Jung Hoon Choi, In Koo Hwang, Goo Jang and Yeo Sung Yoon
    Citation: Laboratory Animal Research 2017 33:3302114
    Content type: Case Report Published on:

  41. Ginsenosides from Panax ginseng are well known for their diverse pharmacological effects including antithrombotic activity. Since adventitious roots of mountain ginseng (ARMG) also contain various ginsenosides, b...

    Authors: Young-Hwan Ban, Yeseul Cha, Jieun Choi, Eun Suk An, Ji Young Lee, Nu Ry Han, Da Woom Seo, Gooyoung Jung, Da-Hye Jeong, Man Hee Rhee, Ehn-Kyoung Choi and Yun-Bae Kim
    Citation: Laboratory Animal Research 2017 33:3302105
    Content type: OriginalPaper Published on:

  43. The objective of this study was to determine the effect of ionizing radiation (IR) exposure of parents on carcinogenesis of the next generation focusing on the epigenetic perspective to clarify the relationshi...

    Authors: Lan Li, Jong-Hyun Kim, Hee-Tae Park, Jae-Hoon Lee, Min-Koo Park, Ji-Won Lee, Jeong-Chan Lee and Min-Jae Lee
    Citation: Laboratory Animal Research 2017 33:3302092
    Content type: OriginalPaper Published on:

  44. The usage of essential oils as antimicrobial agents is gaining attention. Besides, pet turtles were known to harbor a range of pathogenic bacteria while the turtle keeping is a growing trend worldwide.The curr...

    Authors: B. C. J. De Silva, Won-Gi Jung, Sabrina Hossain, S. H. M. P. Wimalasena, H. N. K. S. Pathirana and Gang-Joon Heo
    Citation: Laboratory Animal Research 2017 33:3302084
    Content type: OriginalPaper Published on:

  45. Chronic obstructive pulmonary diseases (COPD) is an important disease featured as intense inflammation, protease imbalance, and air flow limitation and mainly induced by cigarette smoke (CS). In present study,...

    Authors: Je-Won Ko, Na-Rae Shin, Sung-Hyeuk Park, Joong-Sun Kim, Young-Kwon Cho, Jong-Choon Kim, In-Sik Shin and Dong-Ho Shin
    Citation: Laboratory Animal Research 2017 33:3302076
    Content type: OriginalPaper Published on:

  46. The genetically engineered mice require special husbandry care and are mainly housed in Individually Ventilated Cage (IVC) systems and Static Micro Isolator Cages (SMIC) to minimize the risk for spreading unde...

    Authors: Shikha Yadav, Inderjeet Yadav, Kunal Pratap, Pradeep Kumar Tiwari and Vijay Pal Singh
    Citation: Laboratory Animal Research 2017 33:3302068
    Content type: OriginalPaper Published on:

  47. The inhibitory effects of Asparagus cochinchinensis against inflammatory response induced by lipopolysaccharide (LPS), substance P and phthalic anhydride (PA) treatment were recently reported for some cell lines ...

    Authors: Ji Eun Sung, Jun Young Choi, Ji Eun Kim, Hyun Ah Lee, Woo Bin Yun, Jin Ju Park, Hye Ryeong Kim, Bo Ram Song, Dong Seob Kim, Chung Yeoul Lee, Hee Seob Lee, Yong Lim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3302057
    Content type: OriginalPaper Published on:

  48. Turtle-borne Salmonella enterica owns significance as a leading cause in human salmonellosis. The current study aimed to determine the quinolone susceptibility and the genetic characteristics of 21 strains of S. ...

    Authors: B. C. J. De Silva, Sabrina Hossain, S. H. M. P. Wimalasena, H. N. K. S. Pathirana, Mitchell Wendt and Gang-Joon Heo
    Citation: Laboratory Animal Research 2017 33:3302049
    Content type: OriginalPaper Published on:

  49. HemoHIM, herbal preparation has designed for immune system recovery. We investigated the antiinflammatory effect of HemoHIM on cigarette smoke (CS) and lipopolysaccharide (LPS) induced chronic obstructive pulm...

    Authors: Na-Rae Shin, Sung-Ho Kim, Je-Won Ko, Sung-Hyeuk Park, In-Chul Lee, Jung-Min Ryu, Jong-Choon Kim and In-Sik Shin
    Citation: Laboratory Animal Research 2017 33:3301040
    Content type: OriginalPaper Published on:

  50. The purpose of this study was to investigate the immunomodulatory activity of ice plant (Mesembryanthemum crystallinum) extract (IPE) in vitro and in vivo. Raji (a human B cell line) and Jurkat (a human T cell li...

    Authors: Joo-Hee Choi, Sung-Gang Jo, Seoung-Ki Jung, Woo-Tae Park, Keun-Young Kim, Yong-Wook Park and Jong-Hwan Park
    Citation: Laboratory Animal Research 2017 33:3301032
    Content type: OriginalPaper Published on:
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  • Laboratory Animal Research is the official journal of the Korean Association for Laboratory Animal Science. KALAS was established in 1985 in order to discuss the knowledge of the experiment, and promote the science and technology in laboratory animal sciences.

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Laboratory Animal Research

ISSN: 2233-7660