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  1. Cognitive impairment responses are important research topics in the study of degenerative brain diseases as well as in understanding of human mental activities. To compare response to scopolamine (SPL)-induced...

    Authors: Woo Bin Yoon, Hyeon Jun Choi, Ji Eun Kim, Ji Won Park, Mi Ju Kang, Su Ji Bae, Young Ju Lee, You Sang Choi, Kil Soo Kim, Young-Suk Jung, Joon-Yong Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2018 34:3404317
  2. Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed ...

    Authors: Hajin Nam, Yoo Yeon Kim, Boyoung Kim, Won Kee Yoon, Hyoung-Chin Kim and Jun Gyo Suh
    Citation: Laboratory Animal Research 2018 34:3404311
  3. Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various diseases, including c...

    Authors: HyunJeong Lee, Joo-Il Kim, Jin-Sung Park, Jae-il Roh, Jaehoon Lee, Byeong-Cheol Kang and Han-Woong Lee
    Citation: Laboratory Animal Research 2018 34:3404279
  4. This study was conducted to compare the anesthetic effects of 2,2,2-tribromoethanol (TBE, Avertin®) in ICR mice obtained from three different sources. TBE (2.5%) was intraperitoneally injected at three doses: ...

    Authors: Mi Ree Lee, Hye Rin Suh, Myeong Whan Kim, Joon Young Cho, Hyun Keun Song, Young Suk Jung, Dae Youn Hwang and Kil Soo Kim
    Citation: Laboratory Animal Research 2018 34:3404270
  5. Trefoil factor 1 (TFF1, also known as pS2) is strongly expressed in the gastrointestinal mucosa and plays a critical role in the differentiation of gastric glands. Since approximately 50% of all human gastric can...

    Authors: Hyejeong Kim, Haengdueng Jeong, Yejin Cho, Jaehoon Lee, Ki Taek Nam and Han-Woong Lee
    Citation: Laboratory Animal Research 2018 34:3404257
  6. O-2-18F-fluoroethyl-l-tyrosine ([18F]FET) has been widely used for glioblastomas (GBM) in clinical practice, although evaluation of its applicability in non-clinical research is still lacking. The objective of th...

    Authors: Ok-Sun Kim, Jang Woo Park, Eun Sang Lee, Ran Ji Yoo, Won-Il Kim, Kyo Chul Lee, Jae Hoon Shim and Hye Kyung Chung
    Citation: Laboratory Animal Research 2018 34:3404248
  7. Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized that Bacopa monnieri extract (...

    Authors: Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Woosuk Kim, Jong Whi Kim, Dae Young Yoo, Yeo Sung Yoon, In Koo Hwang and Dae Won Kim
    Citation: Laboratory Animal Research 2018 34:3404239
  8. Animal models have been used to elucidate the pathophysiology of varying diseases and to provide insight into potential targets for therapeutic intervention. Although alternatives to animal testing have been p...

    Authors: Seunghyun Lee, Jae-Hwan Kwak, Sou Hyun Kim, Jieun Yun, Joon-Yong Cho, Kilsoo Kim, Daeyeon Hwang and Young-Suk Jung
    Citation: Laboratory Animal Research 2018 34:3404232
  9. The following experiments were designed to examine the effect of serum of spayed dogs on superovulation response in mice and rats. In Experiment 1, female mice at diestrus (n=30) were divided into three equal ...

    Authors: M. H. Nooranizadeh, A. Mogheiseh, M. Kafi, M. Sepehrimanesh and H. Vaseghi
    Citation: Laboratory Animal Research 2018 34:3404211
  10. Hyperglycemia is one of the major risk factors for stroke. Hyperglycemia can lead to a more extensive infarct volume, aggravate neuronal damage after cerebral ischemia. α-Synuclein is especially abundant in ne...

    Authors: Ju-Bin Kang, Dong-Kyun Kim, Dong-Ju Park, Murad-Ali Shah, Myeong-Ok Kim, Eun-Jung Jung, Han-Shin Lee and Phil-Ok Koh
    Citation: Laboratory Animal Research 2018 34:3404195
  11. The different polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene promote variances in diabetes susceptibility in humans. We investigated whether these genotypes also promote differences in diabet...

    Authors: Ching-Fu Tu, Chi-Yun Hsu, Meng-Hwan Lee, Bo-Hui Jiang, Shyh-Forng Guo, Chai-Ching Lin and Tien-Shuh Yang
    Citation: Laboratory Animal Research 2018 34:3404185
  12. In this study, we observed chronological changes in the immunoreactivity and expression level of myelin basic protein (MBP), one of the most abundant proteins in the central nervous system, in the hippocampus ...

    Authors: Sung Min Nam, Hyun Jung Kwon, Woosuk Kim, Jong Whi Kim, Kyu Ri Hahn, Hyo Young Jung, Dae Won Kim, Dae Young Yoo, Je Kyung Seong, In Koo Hwang and Yeo Sung Yoon
    Citation: Laboratory Animal Research 2018 34:3404176
  13. Recombination activating gene-2 (RAG-2) plays a crucial role in the development of lymphocytes by mediating recombination of T cell receptors and immunoglobulins, and loss of RAG-2 causes severe combined immunode...

    Authors: Joo-Il Kim, Jin-Sung Park, Hanna Kim, Soo-Kyung Ryu, Jina Kwak, Euna Kwon, Jun-Won Yun, Ki-Taek Nam, Han-Woong Lee and Byeong-Cheol Kang
    Citation: Laboratory Animal Research 2018 34:3404166
  14. Breast cancer remains the second leading cause of cancer death among woman, worldwide, despite advances in identifying novel targeted therapies and the development of treating strategies. Classification of cli...

    Authors: Mi Kyung Park, Chang Hoon Lee and Ho Lee
    Citation: Laboratory Animal Research 2018 34:3404160
  15. Genetically engineered mouse models are commonly preferred for studying the human disease due to genetic and pathophysiological similarities between mice and humans. In particular, Cre-loxP system is widely used ...

    Authors: Hyeonhui Kim, Minki Kim, Sun-Kyoung Im and Sungsoon Fang
    Citation: Laboratory Animal Research 2018 34:3404147
  16. In the Materials and Methods section, material supply source is incorrectly cited and has been changed upon request of authors. In Acknowledgments, following paragraph would be added by authors’ request.

    Authors: Song-Hee Han, Sung-June Kim, Young Won Yun, Sang Yoon Nam, Hu-Jang Lee and Beom-Jun Lee
    Citation: Laboratory Animal Research 2018 34:3403132

    The original article that this is related to.

  17. Serum levels of the pro-inflammatory apolipoprotein CIII (apoCIII) are increased in type-1 diabetic (T1D) patients and when β-cells are exposed to apoCIII they undergo apoptosis, which can be prevented by an a...

    Authors: Karin Åvall, Per-Olof Berggren and Lisa Juntti-Berggren
    Citation: Laboratory Animal Research 2018 34:3403126
  18. To evaluate the carcinogenicity of p27 knockout (KO) mice with RNA-guided endonuclease (RGENs)-mediated p27 mutant exon I gene (IΔ), alterations in the carcinogenic phenotypes including tumor spectrum, tumor s...

    Authors: Jun Young Choi, Woo Bin Yun, Ji Eun Kim, Mi Rim Lee, Jin Ju Park, Bo Ram Song, Hye Ryeong Kim, Ji Won Park, Mi Ju Kang, Byeong Cheol Kang, Han-Woong Lee and Dae Youn Hwang
    Citation: Laboratory Animal Research 2018 34:3403118
  19. Benign prostate hyperplasia (BPH) is a male reproductive disease that has gained increasing importance in recent years. The present study investigated whether Pycnogenol® (PYC), a standardized French maritime ...

    Authors: Je-Won Ko, So-Won Park, Na-Rae Shin, Woong-Il Kim, Jong-Choon Kim, In-Sik Shin and Dong-Ho Shin
    Citation: Laboratory Animal Research 2018 34:3403111
  20. The butanol extract of Asparagus cochinchinensis roots fermented with Weissella cibaria (BAfW) significantly suppressed the inflammatory response induced by lipopolysaccharide (LPS) treatment in RAW264.7 cells. T...

    Authors: Jun Young Choi, Ji Won Park, Ji Eun Kim, Jin Ju Park, Mi Rim Lee, Bo Ram Song, Mi Ju Kang and Dae Youn Hwang
    Citation: Laboratory Animal Research 2018 34:3403101
  21. Water extract of guibi-tang (GB), a traditional Chinese, Japanese, and Korean herbal medicine, is used to treat memory impairment, insomnia, and peptic ulcers. The aim of this study was to investigate the prot...

    Authors: Na-Rae Shin, Tae-Yang Jung, Chang-Seob Seo, So-Won Park, Je-Won Ko, Jong-Choon Kim and In-Sik Shin
    Citation: Laboratory Animal Research 2018 34:3403092
  22. Hepatitis B virus (HBV) infection remains a major global health problem; indeed, there are 250 million carriers worldwide. The host range of HBV is narrow; therefore, few primates are susceptible to HBV infect...

    Authors: Jeong-Ryul Hwang and Sung-Gyoo Park
    Citation: Laboratory Animal Research 2018 34:3403085
  23. The elimination half-lives of in Interleukin-6 (IL-6) and cytokine-induced neutrophil chemoattractant-1 (CINC-1) in rats after inflammatory stimulation were investigated. Five male Sprague-Dawley rats were use...

    Authors: Takashi Kuribayashi
    Citation: Laboratory Animal Research 2018 34:3402080
  24. Allium hookeri is widely consumed plant as a vegetable and herbal medicine in southeastern Asia. Allium hookeri has been reported antioxidant, improvement of bone health and antidiabetic effects. In the present s...

    Authors: Hyun-A Lee, Sunhwa Hong, Ji-Hyun Yoo, Yungho Chung and Okjin Kim
    Citation: Laboratory Animal Research 2018 34:3402075
  25. The purpose of the study was to investigate the effects of lipid-coated ZnO (LCZ) and the level of LCZ compared with ordinary zinc oxide (ZnO) on antioxidant defense system in the intestine and liver of piglet...

    Authors: Ha-Na Kim, Dong-Gyung Jeon, Chul Young Lee and In-Surk Jang
    Citation: Laboratory Animal Research 2018 34:3402065
  26. In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains using immuno-histochemistry...

    Authors: Kwon Young Lee, Dae Young Yoo, Hyo Young Jung, Loktam Baek, Hangyul Lee, Hyun Jung Kwon, Jin Young Chung, Seok Hoon Kang, Dae Won Kim, In Koo Hwang and Jung Hoon Choi
    Citation: Laboratory Animal Research 2018 34:3402058
  27. Hangover is characterized by a number of unpleasant physical and mental symptoms that occur after heavy alcohol drinking. In addition, consistently excessive alcohol intake is considered as a major reason caus...

    Authors: Jae Young Yu, Hanh Thuy Nguyen, Chul Soon Yong, Hyoung Geun Park, Joon Ho Jun and Jong Oh Kim
    Citation: Laboratory Animal Research 2018 34:3402049

    The Retraction Note to this article has been published in Laboratory Animal Research 2020 36:18

  28. In this article, So-Young Park is inadvertently omitted from the listed author names. In the Acknowledgement section, funding source is incorrectly cited and has been changed upon request of authors.

    Authors: Young-Hwan Ban, Yeseul Cha, Jieun Choi, Eun Suk An, Ji Young Lee, Nu Ry Han, Da Woom Seo, Gooyoung Jung, Da-Hye Jeong, Man Hee Rhee, Ehn-Kyoung Choi and Yun-Bae Kim
    Citation: Laboratory Animal Research 2018 34:3101048

    The original article was published in Laboratory Animal Research 2017 33:Art8

  29. Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria (E.) tenella. This experiment...

    Authors: Sunhwa Hong, Mi-Na Moon, Eun-Kyung Im, Jum-Soon Won, Ji-Hyun Yoo and Okjin Kim
    Citation: Laboratory Animal Research 2018 34:3101044
  30. This study was performed to investigate the effect of a concentrate of fermented wild ginseng root culture (HLJC0701) on memory improvement in the scopolamine (SPL)-induced memory-deficient mouse model. Eight-...

    Authors: Song-Hee Han, Sung-June Kim, Young Won Yun, Sang Yoon Nam, Hu-Jang Lee and Beom-Jun Lee
    Citation: Laboratory Animal Research 2018 34:3101037
  31. This study investigated the anti-cancer potential of a near-infrared fluorescence (NIRF) molecule conjugated with Cetuximab (Cetuximab-NIRF) in six-week-old female BALB/c athymic (nu+/nu+) nude mice. A431 cell...

    Authors: Ji Young Yun, Byung-Hwa Hyun, Sang Yoon Nam, Young Won Yun, Hu-Jang Lee and Beom-Jun Lee
    Citation: Laboratory Animal Research 2018 34:3101030
  32. C57BL/6N mice are inbred strains widely used in biomedical research. Hence, a large amount of basic data has been accumulated. However, in the field of histopathology, spontaneous data for relatively younger m...

    Authors: Do-Yong Park, Byoung-Seok Lee, Woo-Jin Kim, Wan-Jung Im, Ji-Seok Han, Heejin Park, Mi-Jin Yang, Jae-Woo Cho, Da Hee Kim, Su-Cheol Han, Yong-Bum Kim and Hwa-Young Son
    Citation: Laboratory Animal Research 2018 34:3101020
  33. The aim of this study is to evaluate the reporting quality of animal experiments in Korea using the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guideline developed in 2010 to overcome the reproduc...

    Authors: Mi-Hyun Nam, Myung-Sun Chun, Je-Kyung Seong and Hoon-Gi Kim
    Citation: Laboratory Animal Research 2018 34:3101011
  34. Chronic obstructive pulmonary disease (COPD) was the 3rd leading cause of death in 2012 worldwide. It is particularly severe in the elderly, who are at risk of death by coughing, mucous hypersecretion, and finall...

    Authors: Soon-Young Lee, Jin-Ho Cho, Seung Sik Cho, Chun-Sik Bae, Gye-Yeop Kim and Dae-Hun Park
    Citation: Laboratory Animal Research 2018 34:3101001
  35. Quercetin, a natural flavonoid, copiously exists in vegetable, fruits and tea. Quercetin is beneficial to neurodegenerative disorders via its strong anti-oxidant and anti-inflammatory activities. γ-Enolase is ...

    Authors: Seong-Jun Jeon, Myeong-Ok Kim, Fawad Ali-Shah and Phil-Ok Koh
    Citation: Laboratory Animal Research 2018 33:3304308
  36. A correlation between endoplasmic reticulum (ER) stress and laxative effects was first reported in a constipation model treated with an aqueous extract of Liriope platyphylla (AEtLP) roots. To investigate the cor...

    Authors: Ji Eun Kim, Bo Ram Song, Woo Bin Yun, Jun Young Choi, Jin Ju Park, Mi Rim Lee and Dae Youn Hwang
    Citation: Laboratory Animal Research 2018 33:3304298
  37. Thread-embedding therapy has been widely applied for cosmetic purposes such as wrinkle reduction and skin tightening. Particularly, gold thread was reported to support connective tissue regeneration, but, its ...

    Authors: Jong-Hwan Kim, Eun-Young Cho, Euna Kwon, Woo-Ho Kim, Jin-Sung Park, Yong-Soon Lee, Jun-Won Yun and Byeong-Cheol Kang
    Citation: Laboratory Animal Research 2018 33:3304291
  38. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Woo Bin Yun, Hye Ryeong Kim, Ji Eun Kim, Jun Young Choi, Mi Rim Lee, Jin Ju Park, Bo Ram Song, Young Suk Jung, Hyun Keun Song, Joon Young Cho, Kil Soo Kim and Dae Youn Hwang
    Citation: Laboratory Animal Research 2017 33:3304321

    The original article was published in Laboratory Animal Research 2017 33:Art18

  39. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Sou Hyun Kim, Keuk-Jun Kim, Joung-Hee Kim, Jae-Hwan Kwak, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim and Young-Suk Jung
    Citation: Laboratory Animal Research 2017 33:3304319

    The original article was published in Laboratory Animal Research 2017 33:Art16

  40. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Sou Hyun Kim, Yong Lim, Ju Bin Park, Jae-Hwan Kwak, Keuk-Jun Kim, Joung-Hee Kim, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim and Young-Suk Jung
    Citation: Laboratory Animal Research 2017 33:3304318

    The original article was published in Laboratory Animal Research 2017 33:Art15

  41. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Dong-Ju Hwang, Hyun-Keun Song, Kil-Soo Kim, Young-Suk Jung, Dae-Youn Hwang and Joon Young Cho
    Citation: Laboratory Animal Research 2017 33:3304317

    The original article was published in Laboratory Animal Research 2017 33:Art13

  42. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Hye Ryeong Kim, Jun Young Choi, Kil Soo Kim, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2017 33:3304316

    The original article was published in Laboratory Animal Research 2017 33:Art12

  43. One of the authors’ names was misprinted. The author list should be corrected as follows.

    Authors: Jun Young Choi, Hye Ryeong Kim, Kil Soo Kim, Young-Suk Jung, Joon Young Cho, Dae Youn Hwang and Hyun Keun Song
    Citation: Laboratory Animal Research 2017 33:3304315

    The original article was published in Laboratory Animal Research 2017 33:Art11

  44. In the present study, we examined the effects of Dendropanax morbifera Léveille leaf extract (DML) on dgalactose-induced morphological changes in microglia and cytokines, including pro-inflammatory cytokines (int...

    Authors: Kwon Young Lee, Hyo Young Jung, Dae Young Yoo, Woosuk Kim, Jong Whi Kim, Hyun Jung Kwon, Dae Won Kim, Yeo Sung Yoon, In Koo Hwang and Jung Hoon Choi
    Citation: Laboratory Animal Research 2017 33:3304283
  45. Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly us...

    Authors: Tai-Young Hur, Seung-Hoon Lee, Sun-A Ock, Hyuk Song, Hyun-Jung Park, Ran Lee, Si-Heung Sung, Hyunjhung Jhun and Won-Young Lee
    Citation: Laboratory Animal Research 2017 33:3303264

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  • Laboratory Animal Research is the official journal of the Korean Association for Laboratory Animal Science. KALAS was established in 1985 in order to discuss the knowledge of the experiment, and promote the science and technology in laboratory animal sciences.

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